The holiday season is upon us, and what better way to take a little break from the lab than with a fun puzzle? Our December 2025 crossword is filled with festive cheer, seasonal traditions, and holiday-inspired clues — all designed to give your brain a little workout while keeping the mood light.
Whether you’re between experiments, waiting for a run to finish, or just taking a moment for yourself, this puzzle is the perfect way to unwind. It’s a festive twist on our usual lab fun, combining problem-solving with holiday spirit.
Print it out, solve it at your own pace, and enjoy a few minutes of seasonal fun. Even better, it’s a great little challenge to share with colleagues or students for a bit of friendly competition!
From all of us at SeqGen, we hope your holidays are bright, joyful, and filled with moments to relax — and maybe a little puzzle-solving too.
Click the image below to download your printable PDF.
Answers here.