[Quick Summary]
How do you fix short read lengths on a 3730 analyzer? If read lengths drop (e.g., from 1000 bp to 750 bp), it is likely a polymer issue. To resolve this, perform a 60 °C warm water wash and install a fresh bottle of polymer. If this does not restore data quality, you likely have a faulty polymer from a defective production lot. Order a different lot number immediately, perform a second wash, and install the new lot.
