Not reaching “Ready” on your SCIEX Triple Quad 6500+? Vacuum pressure could be the culprit. Seeing flashing LEDs, high Torr readings, or sudden loss of sensitivity? You’re not alone—and the fix may be simpler than you think. This guide answers common questions about vacuum issues on the SCIEX 6500+ and walks you through quick checks to get your system back online.

When it comes to liquid chromatography, the mobile phase plays a critical role in carrying the sample through the chromatography column and into the mass spectrometer.